Developmental Neurobiology

Syllabus
Schedule
Reading List
Term Paper
Examinations
Discussion
Directory
Advice

Reading List

 

Jan 22

Background (from McLoon on Embryology of the nervous system)

·        Kandel et al., Chapter 52, pp. 1019-1027

 

Jan 24

Background (from Lanier on Survey of methods used to alter gene expression)

·        Snove, Rossi (2006) Expressing short hairpin RNAs in vivo. Nat Meth 3:689-695

·      Burger, Nash, Mandel (2005) Recombinant adeno-associated viral vectors in the nervous system. Human Gene Therapy 16:781-791

 

Jan 29

Background (from Letourneau on Induction)

·        Kandel et al., Chapter 52, pp. 1019-1027 (same as for Jan 22)

·        Stern (2005) Neural induction: old problem, new findings, yet more questions. Development 132:2007-2021

 

Jan 31

Background (from Koyano on Regionalization of the neural tube)

·        Kandel et al., Chapter 52, pp. 1027-1036

Discussion (from Letourneau on Induction)

·        Kuroda et al. (2005) Default neural induction: Neuralization of dissociated Xenopus cells is mediated by RAS/MAPK activation. Genes Dev 19:1022-1027

 

Feb 5

Background (from Koyano on Determination of cell fate)

·        Kandel et al., Chapter 53, pp. 1041-1052

Discussion (from Koyano on Regionalization of the neural tube)

·       Dasen et al. (2003) Motor neuron columnar fate imposed by sequential phases of Hox-c activity. Nature 425:926-933 [note Suppl. Fig. 1]

 

Feb 7

Background (from McLoon on Cell division and cell lineage)

·        Cremisi et al. (2003) Cell cycle and cell fate interactions in neural development. Curr Opin Neurobiol 13:26-33

·        Kriegstein, Noctor, Martinez-Cerdeno (2006) Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion. Nat. Rev. Neurosci. 7:883-890

Discussion (from Koyano on Determination of cell fate)

·        Muroyama et al. (2005) Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube. Nature 438:360-3

 

Feb 12

Background (from McLoon on Neural crest cell migration)

·        Krull (2001) Segmental organization of neural crest migration. Mech Dev 105:37-45

Discussion (from McLoon on Cell division and cell lineage)

·        Quinn et al. (2007) Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism. Dev Biol 302:50-65

 

Feb 14

Background (from McLoon on Cell migration in the CNS)

·        Nadarajah, Parnavelas (2002) Modes of neuronal migration in the developing cerebral cortex. Nat Rev Neurosci 3:423-432

Discussion (from McLoon on Neural crest cell migration)

·        Jia et al. (2005) Slit/Robo signaling is necessary to confine early neural crest cells to the ventral migratory pathway in the trunk. Dev Biol 282:411-421

 

Feb 19

Background (from Lanier on Intrinsic mechanisms of neuronal migration)

·        Ayala et al. (2007) Trekking across the brain: The journey of neuronal migration. Cell 128:29-43

·        Higginbotham, Gleeson (2007) The centrosome in neuronal development. Trends Neurosci 30:276-283

Discussion (from McLoon on Cell migration in the CNS)

·        Elias, Wang, Kriegstein (2007) Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448:901-907

 

Feb 21

Background (from Lanier on Neurite initiation & growth cone motility)

·        Dent, Gertler (2003) Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 40:209-227

·      Yoshimura, Arimura, Kaibuchi (2006) Signaling networks in neuronal polarization. J Neurosci 26:10626-10630

Discussion (from Lanier on Intrinsic mechanisms of neuronal migration)

·        Belvindrah et al. (2007) Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex.  J Neurosci  27:133854-13865

 

Feb 26

Background (from Letourneau on Axon guidance I)

·        Kandel et al., Chapter 54, pp. 1063-1086

Discussion (from Lanier on Neurite initiation & growth cone motility)

·        Dent et al. (2007) Filopodia are required for cortical neurite initiation. Nat Cell Biol 9:1347-1359

 

Feb 28

Background (from Letourneau on Axon guidance II)

·        Chilton (2006) Molecular mechanisms of axon guidance. Developmental Biology 292:13-24

Discussion (from Letourneau on Axon guidance I)

·         Lopez-Bendito et al. (2007) Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. J Neurosci 27:3395-3407

 

Mar 4

Background (from Letourneau on Synapse formation & receptor clustering)

·        Kandel et al., Chapter 55, pp. 1087-1108

·        Waites et al. (2005) Mechanisms of vertebrate synaptogenesis. Annu Rev Neurosci 28:251-274

Discussion (from Letourneau on Axon guidance II)

·        Imai et al. (2006) Oderant receptor-derived cAMP signals direct axonal targeting. Science 314:657-661

 

Mar 6

Discussion (from Letourneau on Synapse formation & receptor clustering)

·         Nam, Chen (2005) Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter. Proc Natl Acad Sci USA 102:6137-6142

 

Mar 25

Background (from McLoon on Specificity of connections)

·        Flanagan (2006) Neural map specification by gradients. Curr Opin Neurobiol 16:1-8

·        Komiyama, Luo (2006) Development of wiring specificity in the olfactory system. Curr Opin Neurobiol 16:1-7

 

Mar 27

Background (from Nakagawa on Refinement of connections I)

·        Luo, O’Leary (2005) Axon retraction and degeneration in development and disease. Annu Rev Neurosci 28:127-56

Discussion (from McLoon on Specificity of connections)

·        Hodge et al. (2007) Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron 55:572-586

 

Apr 1

Background (from Nakagawa on Refinement of connections II)

·        Huberman (2007) Mechanisms of eye-specific visual circuit development. Curr Opin Neurobiol 17:73-80

·       Spitzer (2006) Electrical activity in early neuronal development. Nature 444:707-12

Discussion (from Nakagawa on Refinement of connections I)

·        Hoopfer et al. (2006) Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning. Neuron 50:883-95

 

Apr 3

Background (from Nakagawa on Development of dendrites)

·        Parrish et al. (2007) Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu Rev Neurosci 30:399-423

Discussion (from Nakagawa on Refinement of connections II)

·        Pfeiffenberger et al. (2005) Ephrin-As and neural activity are required for eye-specific patterning during retinogeniculate mapping. Nat Neurosci 8:1022-7

 

Apr 8

Background (from McLoon on Developmental cell death)

·        Davies (2003) Regulation of neuronal survival and death by extracellular signals during development. EMBO J 22:2537-2545

Discussion (from Nakagawa on Development of dendrites)

·        Ohshima et al. (2007) Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development 134:2273-82

 

Apr 10

Background (from Letourneau on Trophic factors – neurotrophins)

·        Kandel et al., Chapter 53, pp. 1052-1061

·        Reichardt (2006) Neurotrophin-regulated signaling pathways. Phil Trans R Soc B 361:1545-1564

Discussion (from McLoon on Developmental cell death)

·        Vaccari et al. (2006) NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death. Proc Natl Acad Sci USA 103:16971-16976

 

Apr 15

Background (from Letourneau on Trophic factors - other factors)

·        Enomoto (2005) Regulation of neural development by glial cell line-derived neurotrophic factor family ligands. Anatomical Sci Inter 80:42-52

Discussion (from Letourneau on Trophic factors – neurotrophins)

·        Glebova, Ginty (2004) Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J Neurosci 26:743-751

 

Apr 17

Background (from Lanier on Neuron-glia interactions)

·        Ullian et al. (2004) Role for glia in synaptogenesis. Glia 47:209-216

·        Miller, Gauthier (2007) Timing is everything: making neurons versus glia in the developing cortex. Neuron 54:357-369

Discussion (from Letourneau on Trophic factors - other factors)

·        Ozdinler, Macklis (2006) IGF-1 specifically enhances axon outgrowth of corticospinal motor neurons. Nat Neurosci 9:1371-1381

 

Apr 22

Background (from Nick on Development of Behavior)

·        Knudsen (2004) Sensitive periods in the development of the brain and behavior. J Cog Neurosci 16:1412-1425

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·        Hensch (2004) Critical period regulation. Annu Rev Neurosci 27:549-579

Discussion (from Lanier on Neuron-glia interactions)

·        Barnabe-Heider et al. (2005) Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. Neuron 48:253-265

 

Apr 24

Background (from Nakagawa on Neurogenesis in the adult)

·        Emsley et al. (2005) Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors and stem cells. Prog Neurobiol 75:321-341

Discussion (from Nick on Development of Behavior)

·        Khazipov et al. (2004) Early motor activity drives spindle bursts in the developing somatosensory cortex. Nature 432:758-761

 

Apr 29

Background (from McLoon on Reaction to injury and regeneration)

·        Kandel et al., Chapter 55, pp. 1105-1112

·        Yiu, He (2006) Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 7:617-627

Discussion (from Nakagawa on Neurogenesis in the adult)

·        Kohwi, et al., Alvarez-Buylla (2007) A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. J Neurosci 27:6878-91

 

May 6

Discussion (from McLoon on Reaction to injury and regeneration)

·        Yin et al. (2006) Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci 9:845-852